Everything about Tophus totally explained
A
tophus (Latin: "stone", plural
tophi) is a deposit of
crystallised
monosodium urate in people with longstanding
hyperuricemia. At this stage, most have already developed symptoms of the associated crystal arthopathy known as
gout.
Tophi form in the
joints,
cartilage,
bones, and other places throughout the body. Sometimes, tophi break through the
skin and appear as white or yellowish-white, chalky
nodules. Without treatment, tophi may develop on average about ten years after the onset of the
disease, although their first appearance can range from three to forty-two years. They are more apt to appear early in the course of the disease in people who are older in age. In the elderly population, women appear to be at higher risk for tophi than men.
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